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Garlic Butter Shrimp Scampi Lasagna Recipe

If you’re craving something that feels both fancy and comforting, I’ve got just the ticket for you. This Garlic Butter Shrimp Scampi Lasagna Recipe is my absolute favorite way to elevate your usual lasagna game with a buttery, garlicky seafood twist that makes weeknight dinners feel like a celebration. Trust me, once you try this, you’ll keep coming back for more!

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Why You’ll Love This Recipe

  • Bursting with Flavor: The garlic butter sauce perfectly complements the shrimp and cheesy layers, creating irresistible depth.
  • Impressively Easy: It looks gourmet but comes together surprisingly quickly, making it ideal for both special occasions and cozy dinners.
  • Comfort Food Upgrade: You get all the warmth and creaminess of classic lasagna with a fresh, zesty seafood twist.
  • Family Friendly: Even the picky eaters in my house beg for seconds!

Ingredients You’ll Need

The ingredients come together in such a flavorful harmony here — the shrimp scampi sauce brings brightness and a touch of heat, while the cheese mixture adds the right amount of richness and creaminess.

  • Shrimp: Go for large, peeled and deveined shrimp for easy cooking and beautiful presentation.
  • Unsalted Butter: Essential to get that silky garlic butter sauce just right without it being too salty.
  • Garlic: Freshly minced garlic really makes the flavors pop, don’t skimp on it!
  • White Wine: I love the subtle acidity it adds, but you can skip it if you prefer.
  • Lemon Juice: Freshly squeezed adds brightness and balances the buttery flavors perfectly.
  • Red Pepper Flakes: For a gentle kick—feel free to adjust or omit based on your spice tolerance.
  • Fresh Parsley: Adds a fresh, herbaceous note and vibrant color.
  • Lasagna Noodles: Classic no-boil noodles work fine, but I prefer cooking regular ones al dente for perfect layering.
  • Ricotta Cheese: Creamy base that softens the dish and makes it decadently smooth.
  • Mozzarella Cheese: For that gooey melt we all crave.
  • Parmesan Cheese: Adds a nutty, savory finish that’s absolutely essential.
  • Eggs: Help bind the cheese mixture so layers hold together beautifully.
  • Italian Seasoning: A blend that adds classic Italian warmth and complexity.
  • Nutmeg (optional): Just a pinch enhances the cheese mixture without overpowering—trust me, it’s a game changer.
  • Heavy Cream: Spill it over the layers for creamy, melt-in-your-mouth goodness.
Note: You’ll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Variations

I love experimenting with this Garlic Butter Shrimp Scampi Lasagna Recipe to suit different moods and guests. Feel free to make it your own — that’s the beauty of cooking after all!

  • Veggie Boost: I sometimes add sautéed spinach or artichokes between the layers for extra depth and color, and my family doesn’t even notice they’re getting their greens.
  • Spicy Kick: If you like it hotter, double the red pepper flakes or add chopped jalapeños to the shrimp scampi step. Just be sure to taste as you go.
  • Wine-Free Option: Skip the white wine and substitute with a bit more lemon juice or chicken broth—they maintain brightness without alcohol.
  • Gluten-Free Version: Use gluten-free lasagna noodles, and you’re all set for family or friends with dietary needs.

How to Make Garlic Butter Shrimp Scampi Lasagna Recipe

Step 1: Make That Perfect Garlic Butter Shrimp Scampi

Start by melting butter in a big skillet over medium heat. When it’s all melted and shimmering, toss in your minced garlic—this is the moment the kitchen fills with that unbeatable aroma, usually 1-2 minutes is enough so it doesn’t burn. Add in the shrimp, cooking 2-3 minutes per side until pink and opaque; you’ll want to keep an eye so they don’t overcook and get rubbery. Splash in the white wine and lemon juice, then sprinkle a pinch of red pepper flakes, salt, and pepper. Let everything meld together for a couple more minutes before stirring in fresh parsley. Set this fluffy, buttery goodness aside while you prep the noodles and cheese.

Step 2: Cook Your Lasagna Noodles Just Right

I recommend cooking your noodles until al dente according to the package instructions so they hold their shape under all that sauce and cheese but don’t turn mushy after baking. Drain them well and lay them flat on a clean, lightly oiled surface to prevent sticking. Trust me—this step saves you from a lasagna disaster later!

Step 3: Whip Up the Cheesy Ricotta Mixture

In a medium bowl, mix ricotta, mozzarella, Parmesan, eggs, Italian seasoning, and that pinch of nutmeg if you’re using it. The eggs act like glue here, helping the cheese set nicely once baked. Stir until everything is combined and creamy—this mix is going to be your lasagna’s luscious heart, so don’t rush.

Step 4: Layer It Like a Pro

Preheat your oven to 375°F (190°C). Grab a 9×13-inch baking dish and start by spreading a thin layer of heavy cream on the bottom. This little trick keeps the noodles moist and brings extra richness. Lay down a layer of noodles, then spread some of that cheesy ricotta mixture on top, followed by a generous layer of shrimp scampi. Keep repeating the layers until everything is used up—ending with noodles on top. Pour the remaining heavy cream over the top layer and sprinkle the rest of your mozzarella and Parmesan cheese. The cream seeps beautifully into the layers as it bakes, so don’t skip it!

Step 5: Bake to Golden, Bubbling Perfection

Cover your dish tightly with foil and bake for 25 minutes. This keeps the moisture in so everything heats evenly. After that, remove the foil and bake for another 10-15 minutes until the top is gorgeously golden and bubbly. When you take it out, let it rest for a few minutes; that’s the magic moment when the lasagna sets and slices beautifully.

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Pro Tips for Making Garlic Butter Shrimp Scampi Lasagna Recipe

  • Don’t Overcook Shrimp: Shrimp cook fast and go from perfect to rubbery quickly—watch them like a hawk during the scampi stage.
  • Balancing Cream and Cheese: Too much heavy cream can dilute flavor, so spread it thinly and evenly for the best texture.
  • Choosing Noodles: I recommend boiling regular lasagna noodles al dente rather than no-boil for that ideal, tender-but-firm bite.
  • Let It Rest: Slicing immediately can cause the lasagna to fall apart—waiting 10 minutes helps everything set beautifully.

How to Serve Garlic Butter Shrimp Scampi Lasagna Recipe

A close-up view of a three-layer lasagna slice sits on a white plate with a white marbled surface underneath. The top layer is golden brown melted cheese with small green herb sprinkles scattered across it. The middle layer shows a creamy white sauce mixed with small pink shrimp pieces and green herbs. The bottom layer is a light yellow pasta sheet visible just above the plate, also dotted with herbs and sauce. The lasagna looks moist and soft, with sauce slightly oozing onto the plate. photo taken with an iphone --ar 4:5 --v 7

Garnishes

I always finish with a sprinkle of fresh chopped parsley for a pop of color and freshness. Sometimes I add a little extra grated Parmesan right before serving for an extra salty, nutty kick that pairs perfectly with the shrimp.

Side Dishes

Because this dish is rich, I like to keep sides light and crisp. A simple green salad with lemon vinaigrette or steamed asparagus complements it beautifully. Garlic bread is optional—you probably won’t need it but it’s a never-fail crowd-pleaser if you want to go all out!

Creative Ways to Present

For holidays or special dinners, I like layering in individual ramekins—makes for a fancy presentation and personalized portions. You can also bake it in smaller dishes and sprinkle some edible flowers on top for wow factor at dinner parties.

Make Ahead and Storage

Storing Leftovers

I store leftover lasagna in airtight containers in the fridge for up to 3 days. It’s surprisingly easy to reheat in the oven or microwave, and the flavors only deepen overnight, making the next-day meal even better in my experience!

Freezing

This Garlic Butter Shrimp Scampi Lasagna Recipe freezes wonderfully. I freeze it in portions wrapped tightly with foil and plastic wrap, and it keeps well for up to 2 months. Just thaw overnight in the fridge before reheating, and you’re set.

Reheating

To keep the texture intact when reheating, I cover the dish loosely with foil and warm it in a 350°F oven until heated through, about 20-25 minutes. This prevents drying out or rubbery shrimp. A splash of extra cream over the top before heating helps maintain that creamy goodness.

FAQs

  1. Can I use frozen shrimp for this Garlic Butter Shrimp Scampi Lasagna Recipe?

    Yes, you can! Just be sure to thaw the shrimp completely and pat them dry before cooking to avoid excess water diluting the sauce. Cooking time remains the same, but keep a close eye to not overcook.

  2. Is there a dairy-free version of this recipe?

    Absolutely, though it requires some swaps. Use dairy-free butter and cream alternatives, plant-based ricotta and mozzarella substitutes, and adjust seasonings to your taste. The flavor won’t be quite the same but still delicious!

  3. Can I prepare this dish ahead of time?

    You can assemble the lasagna a day in advance and store it covered in the fridge. Bake just before serving for the freshest taste. Just allow a little extra baking time if baking from cold.

  4. How spicy does this Garlic Butter Shrimp Scampi Lasagna get?

    The heat is very gentle with the optional red pepper flakes—easily adjustable or removable. If you’re sensitive to spice, just leave them out for a milder but still flavorful dish.

Final Thoughts

I’ve got to tell you, this Garlic Butter Shrimp Scampi Lasagna Recipe has quickly become a beloved staple in my home because it hits the perfect balance of indulgence and freshness. Every bite feels like a special occasion, yet it’s surprisingly simple to put together. So next time you want to wow your family or friends, give this one a go—you’ll be amazed at how quickly it disappears from the table!

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Garlic Butter Shrimp Scampi Lasagna Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.6 from 61 reviews
  • Author: Lauren
  • Prep Time: 20 minutes
  • Cook Time: 45 minutes
  • Total Time: 1 hour 5 minutes
  • Yield: 8 servings
  • Category: Main Course
  • Method: Baking
  • Cuisine: Italian-American

Description

Garlic Butter Shrimp Scampi Lasagna is a decadent and unique twist on traditional lasagna, layering tender shrimp cooked in a garlic butter scampi sauce with creamy ricotta, mozzarella, and Parmesan cheeses, all baked to golden perfection. This luxurious dish combines the zesty, buttery flavors of classic shrimp scampi with the comforting textures of lasagna noodles, creating an impressive meal perfect for special occasions or indulgent dinners.


Ingredients

Shrimp Scampi

  • 1 lb large shrimp, peeled and deveined
  • 4 tablespoons unsalted butter
  • 4 cloves garlic, minced
  • 1/4 cup white wine (optional)
  • 1/4 cup fresh lemon juice
  • 1 teaspoon red pepper flakes (optional for heat)
  • Salt and pepper to taste
  • 2 tablespoons fresh parsley, chopped

Lasagna

  • 12 lasagna noodles
  • 2 cups ricotta cheese
  • 2 cups shredded mozzarella cheese
  • 1 cup grated Parmesan cheese
  • 2 eggs
  • 1 teaspoon Italian seasoning
  • 1/4 teaspoon nutmeg (optional)
  • 2 cups heavy cream
  • 1/2 cup grated Parmesan cheese (for topping)
  • Fresh parsley, chopped for garnish


Instructions

  1. Prepare the Shrimp Scampi: In a large skillet, melt the butter over medium heat. Add the minced garlic and cook for 1-2 minutes until fragrant. Add the shrimp and cook for 2-3 minutes on each side until they turn pink and opaque. Stir in the white wine, lemon juice, red pepper flakes, salt, and pepper. Cook for an additional 2 minutes, then remove from heat. Stir in chopped parsley and set aside.
  2. Cook the Lasagna Noodles: Cook the lasagna noodles according to package instructions until al dente. Drain and set aside to prevent sticking.
  3. Prepare the Cheese Mixture: In a medium bowl, combine ricotta cheese, 1 cup mozzarella, 1 cup Parmesan, eggs, Italian seasoning, and nutmeg (if using). Mix thoroughly until well combined.
  4. Assemble the Lasagna: Preheat oven to 375°F (190°C). In a 9×13-inch baking dish, spread a thin layer of heavy cream on the bottom. Layer lasagna noodles, followed by a layer of ricotta cheese mixture, then a layer of shrimp scampi. Repeat layers until ingredients are used up, finishing with a top layer of noodles. Pour remaining heavy cream over the top and sprinkle with remaining mozzarella and Parmesan cheese.
  5. Bake the Lasagna: Cover the dish with aluminum foil and bake in the oven for 25 minutes. Remove foil and continue baking for 10-15 minutes more, or until the cheese is bubbly and golden brown.
  6. Serve: Allow the lasagna to cool a few minutes before slicing. Garnish with fresh parsley and serve warm for a rich and satisfying meal.

Notes

  • This dish fuses the bright, buttery flavors of shrimp scampi with the creamy, cheesy goodness of lasagna, making it an indulgent upgrade from classic recipes.
  • Use fresh shrimp for the best flavor and texture, but frozen works as well if thoroughly thawed before cooking.
  • White wine is optional but adds depth and acidity to the scampi sauce; you can substitute with extra lemon juice or broth if preferred.
  • Careful not to overcook shrimp to keep them tender and juicy.
  • Allow the lasagna to set slightly after baking for cleaner slices and better presentation.
  • This lasagna is ideal for special occasions or when entertaining guests who appreciate gourmet seafood dishes.

Nutrition

  • Serving Size: 1 slice (1/8 of lasagna)
  • Calories: 520
  • Sugar: 3g
  • Sodium: 630mg
  • Fat: 35g
  • Saturated Fat: 20g
  • Unsaturated Fat: 12g
  • Trans Fat: 0.5g
  • Carbohydrates: 28g
  • Fiber: 2g
  • Protein: 28g
  • Cholesterol: 195mg

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